PedAM

Pediatric Disease Annotations & Medicines


	spinal cord injury

Disease ID	1181
Disease	spinal cord injury
Definition	Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
Synonym	cord injuries, spinal cord injury, spinal cord trauma, spinal cord traumas, spinal inj spinal cord injuries, spinal cord injury, spinal cord injury-spinal cord myelopathies, traumatic myelopathy, traumatic sci - spinal cord injury spinal cord inj spinal cord injuries spinal cord injuries [disease/finding] spinal cord injury (disorder) spinal cord injury, nos spinal cord trauma spinal cord traumas trauma, spinal cord traumas, spinal cord traumatic myelopathies traumatic myelopathy
Orphanet	ORPHANET:90058
UMLS	C0037929
MeSH	D013119
SNOMED-CT	SNOMEDCT_US_2016_09_01:90584004
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:97) C0011127 \| pressure ulcers \| 28 C0005697 \| neurogenic bladder \| 24 C0030486 \| paraplegia \| 23 C0034372 \| tetraplegia \| 12 C0011570 \| depression \| 11 C0034372 \| quadriplegia \| 8 C2004461 \| bowel dysfunction \| 7 C0029456 \| osteoporosis \| 6 C0005697 \| neuropathic bladder \| 6 C0695242 \| neurogenic bowel \| 6 C0005684 \| bladder cancer \| 6 C0028754 \| obesity \| 5 C0021359 \| infertility \| 3 C0028754 \| adiposity \| 3 C0033953 \| sexual dysfunction \| 3 C0003467 \| anxiety \| 3 C0026846 \| muscle atrophy \| 2 C0005683 \| bladder stone \| 2 C0021359 \| infertile \| 2 C0033581 \| prostatitis \| 2 C0004659 \| bacteriuria \| 2 C1145670 \| respiratory failure \| 2 C0042580 \| vesicoureteric reflux \| 2 C0341747 \| detrusor sphincter dyssynergia \| 2 C0040053 \| thrombosis \| 2 C0080178 \| spina bifida \| 2 C0343386 \| clostridium difficile infection \| 2 C0037928 \| myelopathy \| 2 C0748023 \| bacterial prostatitis \| 2 C0009806 \| constipation \| 1 C0022116 \| ischemia \| 1 C0032285 \| pneumonia \| 1 C0022821 \| kyphosis \| 1 C0158252 \| intervertebral disc disease \| 1 C0014544 \| epilepsy \| 1 C0035222 \| acute respiratory distress syndrome \| 1 C0015645 \| fasciitis \| 1 C0038436 \| posttraumatic stress disorder \| 1 C0042373 \| vascular disorders \| 1 C0018799 \| heart disease \| 1 C0031117 \| peripheral neuropathy \| 1 C0037944 \| spinal stenosis \| 1 C0162429 \| malnourished \| 1 C0036439 \| scoliosis \| 1 C0025202 \| melanoma \| 1 C0004936 \| mental disorders \| 1 C0010068 \| coronary heart disease \| 1 C0004096 \| asthma \| 1 C0037856 \| testicular torsion \| 1 C0029443 \| osteomyelitis \| 1 C0042580 \| vesicoureteral reflux \| 1 C0007222 \| cardiovascular disorders \| 1 C0242350 \| erectile dysfunction \| 1 C0004153 \| atherosclerosis \| 1 C0010692 \| bladder inflammation \| 1 C0026975 \| myelitis \| 1 C0042373 \| vascular disorder \| 1 C0035258 \| restless legs syndrome (rls) \| 1 C0151740 \| increased intracranial pressure \| 1 C0030446 \| paralytic ileus \| 1 C0011127 \| decubitus \| 1 C1258215 \| ileus \| 1 C0242966 \| systemic inflammatory response syndrome \| 1 C0002871 \| anemia \| 1 C0020676 \| hypothyroidism \| 1 C0026603 \| motion sickness \| 1 C0019158 \| hepatitis \| 1 C0003864 \| arthritis \| 1 C0376358 \| prostate cancer \| 1 C0238124 \| necrotizing fasciitis \| 1 C0019163 \| hepatitis b infection \| 1 C0001418 \| adenocarcinoma \| 1 C0026846 \| muscular atrophy \| 1 C0014121 \| infective endocarditis \| 1 C0019163 \| hepatitis b \| 1 C0022408 \| arthrosis \| 1 C0442874 \| neuropathy \| 1 C0001080 \| achondroplastic dwarf \| 1 C0151744 \| myocardial ischemia \| 1 C0851578 \| sleep disorders \| 1 C0025289 \| meningitis \| 1 C0010692 \| cystitis \| 1 C0162429 \| malnutrition \| 1 C0020295 \| hydronephrosis \| 1 C0014118 \| endocarditis \| 1 C0302592 \| cervical ca \| 1 C0007789 \| cerebral palsy \| 1 C0011847 \| diabetes \| 1 C0270612 \| leukoencephalopathy \| 1 C0039144 \| syringomyelia \| 1 C0700101 \| urethral ca \| 1 C0152025 \| polyneuropathy \| 1 C0035309 \| retinopathy \| 1 C0751416 \| pelvic cancer \| 1 C0003486 \| aortic aneurysm \| 1 C0011127 \| pressure sores \| 1 C0155502 \| benign paroxysmal positional vertigo \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:4) 239 \| ALOX12 \| infer 348 \| APOE \| infer 627 \| BDNF \| infer 4814 \| NINJ1 \| infer
Text Mined Gene	(Waiting for update.)
Locus	(Waiting for update.)

Disease ID	1181
Disease	spinal cord injury
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:130) HP:0012531 \| Pain \| 60 HP:0012399 \| Bedsore \| 34 HP:0001257 \| Spasticity \| 29 HP:0000011 \| Neurogenic bladder \| 24 HP:0010550 \| Paraplegia \| 23 HP:0002445 \| Paralysis of all four limbs \| 20 HP:0003470 \| Inability to move \| 17 HP:0000010 \| Frequent urinary tract infections \| 12 HP:0000716 \| Depression \| 11 HP:0012378 \| Fatigue \| 9 HP:0011986 \| Ectopic bone formation \| 8 HP:0002459 \| Dysautonomia \| 7 HP:0000020 \| Bladder incontinence \| 7 HP:0010867 \| Dyssynergia \| 7 HP:0012532 \| Chronic pain \| 7 HP:0000939 \| Osteoporosis \| 6 HP:0009725 \| Bladder neoplasm \| 6 HP:0002527 \| Falls \| 5 HP:0001513 \| Obesity \| 5 HP:0000969 \| Dropsy \| 5 HP:0001945 \| Fever \| 4 HP:0002045 \| Abnormally low body temperature \| 4 HP:0012735 \| Coughing \| 3 HP:0001347 \| Hyperreflexia \| 3 HP:0003202 \| Neurogenic muscle atrophy, especially in the lower limbs \| 3 HP:0001907 \| Thromboembolic disease \| 3 HP:0000789 \| Infertility \| 3 HP:0011096 \| Demyelination \| 3 HP:0000739 \| Anxiety \| 3 HP:0002625 \| Blood clot in a deep vein \| 2 HP:0002902 \| Hyponatremia \| 2 HP:0010474 \| Bladder stones \| 2 HP:0003287 \| Abnormality of mitochondrial metabolism \| 2 HP:0000024 \| Inflammation of the prostate \| 2 HP:0011675 \| Arrhythmias \| 2 HP:0002196 \| Myelopathy \| 2 HP:0000076 \| Vesicoureteric reflux \| 2 HP:0006597 \| Paralyzed diaphragm \| 2 HP:0002529 \| Neuronal loss in central nervous system \| 2 HP:0002414 \| Spina bifida \| 2 HP:0030834 \| Shoulder pain \| 2 HP:0012461 \| Bacteria in urine \| 2 HP:0002104 \| Absence of spontaneous respiration \| 2 HP:0002615 \| Low blood pressure \| 2 HP:0012533 \| Allodynia \| 2 HP:0003450 \| Regenerative activity on nerve biopsy \| 2 HP:0002013 \| Emesis \| 2 HP:0002878 \| Respiratory failure \| 2 HP:0001278 \| Orthostatic hypotension \| 2 HP:0100813 \| Testicular torsion \| 1 HP:0003467 \| Atlantoaxial instability \| 1 HP:0001369 \| Arthritis \| 1 HP:0002617 \| Aneurysmal dilatation \| 1 HP:0002019 \| Dyschezia \| 1 HP:0000787 \| Renal calculi \| 1 HP:0001297 \| Cerebral vascular events \| 1 HP:0012486 \| Inflammation of spinal cord \| 1 HP:0006859 \| Posterior leukoencephalopathy \| 1 HP:0002590 \| Paralytic ileus \| 1 HP:0002120 \| Cerebral cortical atrophy \| 1 HP:0001919 \| Acute renal failure \| 1 HP:0002578 \| Gastroparesis \| 1 HP:0002754 \| Bone infection \| 1 HP:0002344 \| Progressive neurologic deterioration \| 1 HP:0002647 \| Aortic dissection \| 1 HP:0004395 \| Malnutrition \| 1 HP:0001649 \| Tachycardia \| 1 HP:0009830 \| Peripheral neuritis \| 1 HP:0002835 \| Aspiration \| 1 HP:0002664 \| Neoplasia \| 1 HP:0002871 \| Central apnea \| 1 HP:0100021 \| Cerebral palsy \| 1 HP:0002321 \| Vertigo \| 1 HP:0008462 \| Cervical instability \| 1 HP:0012115 \| Liver inflammation \| 1 HP:0003447 \| Axonal loss \| 1 HP:0000821 \| Underactive thyroid \| 1 HP:0000079 \| Urinary tract anomalies \| 1 HP:0002025 \| Narrowing of anal opening \| 1 HP:0004936 \| Blood clot in vein \| 1 HP:0100758 \| Gangrene \| 1 HP:0002516 \| Intracranial pressure elevation \| 1 HP:0002099 \| Asthma \| 1 HP:0001250 \| Seizures \| 1 HP:0005952 \| Decreased lung function \| 1 HP:0000047 \| Hypospadias \| 1 HP:0012879 \| Ejaculatory incompetence \| 1 HP:0100699 \| Scarring \| 1 HP:0003477 \| Peripheral axonal neuropathy \| 1 HP:0002808 \| Gibbus deformity \| 1 HP:0005110 \| Atrial fibrillation \| 1 HP:0001288 \| Gait disturbance \| 1 HP:0200119 \| Acute liver inflammation \| 1 HP:0030014 \| Female sexual dysfunction \| 1 HP:0002273 \| Tetraparesis \| 1 HP:0001276 \| Hypertonia \| 1 HP:0012743 \| Central obesity \| 1 HP:0000126 \| Hydronephrosis \| 1 HP:0000488 \| Noninflammatory retina disease \| 1 HP:0002090 \| Pneumonia \| 1 HP:0001324 \| Muscular weakness \| 1 HP:0000016 \| Urinary retention \| 1 HP:0002018 \| Nausea \| 1 HP:0003073 \| Hypoalbuminaemia \| 1 HP:0001903 \| Anemia \| 1 HP:0012216 \| Entrapment neuropathy of suprascapular nerve \| 1 HP:0002621 \| Atherosclerosis \| 1 HP:0002747 \| Respiratory distress due to muscle weakness \| 1 HP:0003401 \| Paresthesia \| 1 HP:0012416 \| Hypercarbia \| 1 HP:0002947 \| Cervical kyphosis \| 1 HP:0012125 \| Prostate cancer \| 1 HP:0001695 \| Cardiac arrest \| 1 HP:0002595 \| Gastrointestinal atony \| 1 HP:0003396 \| Syringomyelia \| 1 HP:0002352 \| Leukoencephalopathy \| 1 HP:0009763 \| Limb pain \| 1 HP:0002017 \| Nausea and vomiting \| 1 HP:0003416 \| Spinal canal stenosis \| 1 HP:0001271 \| Polyneuropathy \| 1 HP:0100537 \| Inflammation of the fascia \| 1 HP:0002318 \| Cervical myelopathy \| 1 HP:0000802 \| Erectile dysfunction \| 1 HP:0002861 \| Melanoma \| 1 HP:0005162 \| Left ventricular impairment \| 1 HP:0002027 \| Abdominal pain \| 1 HP:0002948 \| Fusion of vertebral bodies \| 1 HP:0100543 \| Cognitive deficits \| 1 HP:0100310 \| Extradural hematoma \| 1 HP:0002650 \| Scoliosis \| 1

Disease ID	1181
Disease	spinal cord injury
Manually Symptom	(Waiting for update.)
Text Mined Symptom	(Waiting for update.)

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:7)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0037929	baclofen	D001418	1134-47-0	spinal cord injuries	MESH:D013119	therapeutic	19240673
C0037929	bupivacaine	D002045	2180-92-9	spinal cord injuries	MESH:D013119	marker/mechanism	9794061
C0037929	indomethacin	D007213	53-86-1	spinal cord injuries	MESH:D013119	therapeutic	8157128
C0037929	montelukast	C093875	158966-92-8	spinal cord injuries	MESH:D013119	therapeutic	18059327
C0037929	progesterone	D011374	57-83-0	spinal cord injuries	MESH:D013119	therapeutic	15862959
C0037929	rosiglitazone	C089730	-	spinal cord injuries	MESH:D013119	therapeutic	21206444
C0037929	theophylline	D013806	58-55-9	spinal cord injuries	MESH:D013119	therapeutic	12426040

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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